Original Research Article I Volume 7 I Issue 4 I 2019

Molecular docking of flavonoids from Rumex vesicarius with FOXO1 target related to Diabetes mellitus

Rakesh Davella and Estari Mamidala

Biolife; 2019, 7(4), pp 7-13



Rumex vesicarius flavonoids were taken as ligands for molecular docking. The molecular target, FOXO1 whose crystallographic structures is available on the PDB database as 3CO7, 3CO6 and 3CO7 were used for the docking analysis using the Autodock software. The objective of this study is the evaluation of Rumex vesicarius flavonoids for anti-T2DM activity. The docking studies of the ligands of Rumex vesicarius flavonoids with FOXO1 target showed that Rumex vesicarius flavonoids are good molecules which dock well with FOXO1 target related to diabetes mellitus.


Docking, FOXO1, Rumex vesicarius, Diabetes mellitus.


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Article Dates:

Received: 2 October 2029; Accepted: 18 November 2019; Published: 27 November 2019

How To Cite:

Rakesh Davella, & Estari Mamidala. (2022). Molecular docking of flavonoids from Rumex vesicariuswith FOXO1 target related to Diabetes mellitus. Biolife, 7(4), 7–13. https://doi.org/10.5281/zenodo.7404151

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